Aripiprazole augmentation in poor insight obsessive-compulsive disorder: a case report

نویسندگان

  • Michele Fornaro
  • Filippo Gabrielli
  • Chiara Mattei
  • Valentina Vinciguerra
  • Pantaleo Fornaro
چکیده

BACKGROUND Obsessive-compulsive disorder is associated with a relevant impairment in social and interpersonal functioning and severe disability. This seems to be particularly true for the poor insight subtype, characterised by a lack of consciousness of illness and, consequently, compliance with treatment. Poor responsiveness to serotonergic drugs in poor insight obsessive-compulsive patients may also require an augmentation therapy with atypical antipsychotics. METHODS We reviewed a case in which a patient with a long history of poor insight obsessive-compulsive disorder was treated with a high dosage of serotonin reuptake inhibitors. RESULTS The treatment resulted in a poor outcome. This patient was therefore augmentated with aripiprazole. CONCLUSION Doctors should consider aripiprazole as a possible augmentation strategy for serotonergic poor responder obsessive-compulsive patients, but further research on these subjects is needed.

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عنوان ژورنال:
  • Annals of General Psychiatry

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2008